WebA second laboratory test is the peak/trough serum ratio (PTR). The ratio of peak serum (drawn at 3–4hours post dose) and trough levels (drawn before the next day’s dose) has … WebJan 17, 2000 · In addition to ambulatory blood pressure monitoring data, the calculated trough : peak ratio provides useful information on an agent's ability to provide smooth and consistent blood pressure control. Using such assessments, it has been found that agents with a trough : peak ratio ≥0.50 are better able to control blood pressure over the full ...
Vancomycin Calculator - ClinCalc.com
WebJul 1, 1996 · The mean trough/peak ratios were computed after reconstruction of the curve of the magnitude of blood pressure changes against time. The results showed that once daily administration of ACE inhibitors produced on average ratios higher than 50% with fosinopril (64%), ramipril (50% to 63%), and trandolapril (50% to 100%). WebSep 1, 1998 · T/Ps were calculated as the ratio between average peak and trough changes in the 175 patients. T/Ps were also calculated according to the box-plot approach (median, upper, and lower quartiles and extremes and outliers, the latter indicated by small squares) derived from the individual T/Ps. humanitarian abuse
The Trough-to-Peak Ratio as an Instrument to Evaluate …
WebDec 1, 1995 · According to the usual approach, disregarding interindividual variability, the trough-to-peak ratio was 0.72 for systolic pressure and 0.67 for diastolic pressure. In the … WebAug 12, 2024 · Each category of MMR identified significantly different mean serum levels (peak and trough), peak/trough ratios, and half-lives. When serum levels were analyzed, evidence of subtherapeutic serum levels were found, predominantly in … WebPeak-to-trough ratio ( PTR ), also known as peak-to-trough variation or peak-to-trough fluctuation, is a parameter in pharmacokinetics which is defined as the ratio of C max (peak) concentration and C min (trough) concentration over a dosing interval for a given drug. [1] … humanitarian advance parole